Again as expected, the tretinoin SLNs confirmed a high diploma of localization in pores and skin when evaluated by in vitro pores and skin permeation research. All these effects have been attributed to the encapsulation of tretinoin in nanoparticulate buildings. Barkovic and colleagues (2005) carried out a randomized, placebo-controlled, double-blind medical trial in postmenopausal girls […]
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